The UN Human Rights Council’s Commission of Inquiry on Syria (COI) announced March 6 that it has completed an in-country mission to Damascus as it prepares to brief the Council in Geneva this week. The Commission said it pressed Syria's transitional authorities on accountability, institutional reform, and protections for civil society amid renewed regional volatility.

A group of UN experts warned March 6 that the genocide in Gaza is spilling into the West Bank as a wider war engulfs the region. The experts argued that Israeli policy is designed to coerce Palestinians to leave in both territories. The report also covered occupied East Jerusalem, where between 2021 and 2025 there have been at least 11,555 arrests amid claims of arbitrary detention, 2,386 deportation orders, and 1,732 home demolitions.

The United Nations on March 3 urgently called for civilian protection amid growing violence and instability in the Middle East—and particularly in regard to the ongoing US and Israeli military operations against Iran. The UN urged a thorough investigation into a deadly strike on a girls' school in Iran, and requested the disclosure of all relevant information.

On Feb. 28, the United States and Israel launched coordinated military strikes on Iran, hitting targets in Tehran, Isfahan, Qom and other cities across 24 provinces. Iran's Red Crescent reported at least 201 people killed and 700 injured. US President Donald Trump announced "major combat operations" and openly urged regime change. Iran retaliated by launching missiles at Israel and US military installations across the Gulf States.

The Trump administration appears close to launching military strikes on Iran. The US is amassing a large strike force in the Middle East, including two aircraft carriers, over a dozen warships, and advanced fighter jets, suggesting preparations for a prolonged war. After first threatening military action in January following a protest crackdown in Iran that killed thousands, US officials now say a decision could come within days or weeks, depending on the outcome of now-stalled negotiations over Iran's uranium enrichment and missile development programs. Israeli Prime Minister Benjamin Netanyahu has said any deal must dismantle both programs. Iran's leaders may view forfeiting these means of deterrence against foreign intervention as more dangerous than a war.

Senior UN officials told the Security Council on Feb. 13 that Syria's fragile political transition has gained momentum following a landmark agreement between Damascus and Kurdish authorities in the northeast. Still, they warned that renewed violence in the south, Israeli incursions, and deep humanitarian needs continue to underscore the precarious path to stability.

When US President Donald Trump first proposed establishing a so-called "Board of Peace" to oversee governance of the Gaza Strip for a transitional period back in September, the idea was quickly likened to a form of colonial takeover. The UN nonetheless adopted a Security Council resolution in November giving its blessing to the board's creation—a vote some member states may now regret. The board was officially inaugurated in a Jan. 22 ceremony in Davos, Switzerland, where Trump was attending the World Economic Forum. But Gaza seems almost incidental to its true mission, which appears to be creating a global strongmen's club—led by Trump, potentially for life—to rival, if not replace, the UN itself.

Burma on Jan. 16 began its defense before the International Court of Justice (ICJ) in the ground-breaking genocide case brought by the Gambia, rejecting all allegations of genocide against the Muslim Rohingya minority.