Some of the world's poorest countries, including nations grappling with protracted humanitarian crises, are among those most affected by US President Donald Trump's new trade tariffs regime, which has compounded pre-existing economic strains and debt woes. Asian markets will be particularly hard hit, including imports to the US from Myanmar to be charged at 45%, and Bangladesh at 37%. Big charges were also imposed on fragile economies in the Middle East and North Africa, with Syria at 41%, Libya at 31%, and Iraq at 39%. But among the worst effects will likely be felt in Africa, where Trump's decision has created an "inexplicably cruel situation," according to the Center for Global Development (CGD). "It is hard to fathom that the administration set out to destabilize poor African countries and unclear what they hope to gain," wrote CGD researchers. The tariffs have effectively tanked the African Growth & Opportunity Act (AGOA), which allowed duty-free imports to the US for 32 countries and was credited with helping economic growth. Lesotho and Madagascar could be among the Trump tariffs' biggest losers, CGD predicted. Amid existential financial worries in the international aid sector—triggered by Trump's closure of USAID—economists have also raised the possibility of a global trade war, with far-reaching ramifications for inflation and the cost of living worldwide.

Amnesty International expressed concern April 1 about the lack of political will in South Sudan to address ongoing violations of international human rights law amid escalating violence from both internal and cross-border actors. Reports indicate mounting attacks on civilians, political repression, and the increasing risk of a wider war.

Human Rights Watch (HRW) has called for an immediate investigation into the massacre of dozens of civilians in Burkina Faso's western city of Solenzo on March 10 and 11. In a March 14 statement, HRW noted video footage circulating on social media that implicates pro-government militias in the killings, raising serious concerns about accountability and civilian protection in a country already grappling with widespread violence and human rights abuses. The victims, many of whom belonged to the Fulani ethnic group, were targeted in what appears to be a reprisal attack amid ongoing counterinsurgency operations.

Sudan instituted proceedings against the United Arab Emirates (UAE) before the International Court of Justice (ICJ) on March 6. The claim charges that the UAE has directly supported the paramilitary Rapid Support Forces (RSF) and its associated militia in West Darfur state, violating the Genocide Convention.

Sudan's claim against the UAE is based on weapons seized by the Sudanese Armed Forces in active war zones. Sudanese forces reportedly discovered several passports of Emirati nationals inside armored personnel carriers and 4×4 combat vehicles that originated in the UAE. According to Sudan, this reveals illegal military and logistical support that has allowed the RSF to commit genocidal acts in West Darfur, including the killings of civilians, and the deprivation of access to medical care and basic necessities.

France 24 reports that negotiations are underway between the Qaeda-affiliated JNIM group (the main jihadist coalition in Mali) and the Tuareg-led secessionist Azawad Liberation Front (FLA) over a possible alliance against the Malian army and its Russian mercenary allies. Mali's military government terminated a peace deal with the separatists last year after driving them out of their northern strongholds. The junta has consistently labelled secessionist groups as "terrorists'" and accused them of collusion with jihadists. Separatists deny this, though combatants from both groups share family and community ties, have allied opportunistically at times in the past, and operate in the same areas. According to France 24, current points of negotiation include JNIM softening its demands (perhaps mirroring the strategy of HTS in Syria), especially regarding the application of sharia law, and breaking ties to al-Qaeda. A sticking point may be the FLA's goal of an independent Azawad—the name they give to northern Mali. Intensified fighting in the north over the past year has had severe humanitarian consequences, driving tens of thousands of people to neighboring Mauritania.

South Sudanese troops have deployed around the house of Vice President Riek Machar and arrested officials from his SPLA-IO party, marking one of the most serious threats yet to the peace deal that Machar's group signed with President Salva Kiir in 2018. The arrests follow reports of clashes in northeastern Upper Nile state between the national army and the ethnic Nuer militia known as the White Army, which was allied to Marchar during the 2013-2018 civil war. Machar's spokesperson said they do not know why their officials have been detained, but the information minister accused them of collaborating with the White Army. The International Crisis Group’s senior analyst on South Sudan told Reuters that a delicate balance of power among political elites is now "at risk of collapsing," while the UN and regional bodies warned of "widespread violence" in Upper Nile. Tensions have been mounting since the government's decision last year to postpone long-overdue elections, a delay that critics called a failure to implement the 2018 agreement—which has itself been blamed for fuelling instability. Commanders and politicians compete for power in a transitional government based in the capital, Juba, by fighting local wars in the peripheries.

A UN report released on March 5 found that armed groups operating in the Haut Oubangui region of the Central African Republic (CAR) have been carrying out attacks against Muslim communities and Sudanese refugees, resulting in grave human rights violations. The report, prepared jointly by the UN Human Rights Office and the UN Multidimensional Integrated Stabilization Mission in the Central African Republic (MINUSCA), mainly attributes these attacks to Wagner Ti Azande (WTA), a militia affiliated with the national army.

The Malian Armed Forces command has refuted accusations that soldiers were responsible for an attack that took place on Feb. 17, in which 24 civilians including women and children were killed. The armed forces denied any involvement in the massacre, which is said to have occurred in Tilemsi commune, Gao region. Press reports indicate a caravan of vehicles carrying migrants across the desert was targeted in the attack, which was carried out jointly with Russian mercenaries.