As world leaders meet at the COP27 in Egypt to try to reinvigorate stalled global climate talks, survivors of Pakistan's heaviest flooding in living memory are facing a health crisis, with stagnating floodwaters fuelling a rise in malaria, dengue, and diarrhoea. The unprecedented scale of the disaster—up to $40 billion in economic damage, 1,700 killed since mid-June, eight million displaced, and almost half the country's farmland submerged—has given impetus to calls for COP27 to take up the question of climate reparations.

Syria's cholera outbreak has now spread to every one of the country's 14 provinces, with 24,000 suspected cases and more than 80 deaths since early September. Severe water shortages—exacerbated by war, politics, and climate change—have forced people to drink unsafe water and allowed cholera bacteria to spread in the extremely low Euphrates River. There are other dangerous impacts from what the UN calls an "already dire water crisis" that is likely to get worse: Pastures dry up, and farmers have to sell their livestock. Crop yields are low, prices go up, and more families are forced to skip meals.

Yemen's nationwide truce expired on Oct. 2, as warring parties failed to agree on terms for a renewal. With each side blaming the other for the failure and negotiations ongoing to find common ground, there's concern that fighting will erupt once again on familiar front lines, especially in the central province of Marib and the southwestern city of Taiz. While the gunfire and shelling never completely stopped over the past six months—in some places it got worse—the truce did offer some real respite for Yemenis who have suffered through seven and a half years of war.

More than a month after renewed clashes broke out in Ethiopia's northern Tigray region, there are few signs of de-escalation. A new air-strike hit Tigray's capital of Mekelle on Sept. 23, while the region's ruling party, the Tigray People's Liberation Front (TPLF), accused Eritrea of launching a full-scale offensive in support of the Ethiopian government. There are reports that Eritrea (which has a historical enmity against the TPLF) is mobilizing army reservists, with notices handed out in Asmara, the capital. The return to combat came after a five-month truce that saw back-channel meetings between Mekelle and Addis Ababa but no formal talks. The risk that fresh fighting poses to civilians was underscored by UN investigators, who submitted their first report on the two-year conflict. The investigators accused Ethiopia's government of war crimes in Tigray, and of using starvation as a counterinsurgency tool. Tigrayan forces were also accused of serious human rights abuses.

When mutinous soldiers ousted Burkina Faso's democratically elected president in late January, they vowed to do a better job of securing the Sahelian country from attacks linked to al-Qaeda and the so-called Islamic State. But violence has only increased over the past months, draining public confidence in the junta, threatening coastal West African states, and worsening a humanitarian crisis that has now displaced almost two million people–around one in 10 Burkinabé.

It has been a year since the Taliban took back power—a year since desperate images at Kabul airport went around the world. Over those 12 months, Afghanistan has seen a reduction in conflict, but its economy has collapsed, record numbers are facing hunger, and it's projected that most of the population will soon be below the poverty line.

More than 5 billion people would die of hunger following a full-scale nuclear war between the US and Russia, according to a global study led by Rutgers climate scientists, published Aug. 15 in the journal Nature Food. The team estimated how much sun-blocking soot would enter the atmosphere from firestorms that would be ignited by the detonation of nuclear weapons. Researchers calculated soot dispersal from six scenarios—from a regional India-Pakistan exchange to a large US-Russia war.

Authorities in Sierra Leone imposed a nationwide curfew on Aug. 10, amid anti-government protests, in which a still undetermined number of people have been killed, apparently including at least four police officers. In the capital Freetown, protesters barricaded the streets and clashed with security forces, enraged at a 40% spike in the cost of living. A key demand is the resignation of President Julius Maada Bio, who is on a month-long vacation with his family in London—a trip apparently paid for with misappropriated public funds.