Thousands of Guatemalans took to the streets May 16, demanding the nation's President Otto Pérez Molina step down amid a scandal that has already forced the resignation of his vice president, Roxana Baldetti. Despite rain, protesters marched in 13 cities. Throngs filled the capital's central plaza, where a giant banner read "We are the people." The mobilization was largely leaderless, organized by social media under the hashtag #RenunciaYa (Resign Already). It all blew up in April, when the UN International Commission Against Impunity in Guatemala released findings of an investigation into a customs bribery ring uncovered by Guatemalan prosecutors. Baldetti's private secretary, Juan Carlos Monzón, was named as the ringleader, forcing Baldetti to step down May 8—despite protesting her innocence. Pérez Molina likewise pleads ignorance about the ring, dubbed "La Línea," and pledges a crackdown on corruption. Monzón is on the lam and an Interpol warrant has been issued.

Authorities in Colombia are carrying out their biggest manhunt since the campaign that brought down the legendary Pablo Escobar in 1993. Dario Antonio Usuga AKA "Otoniel" is leader of the Urabeños, a blood-drenched paramilitary network which is said to control much of the cocaine trade in Colombia's northern region of Urabá. The hunt, dubbed the "Siege of Urabá," has mobilized over 2,000 soldiers and National Police troops to the jungles and peasant villages of the northern region. Under a new reward just announced by President Juan Manuel Santos, Otoniel now has a $580,000 price on his head, while his associates "El Galivan," "Nicolas" and "Guagua" each have a price of nearly $200,000.

Identical twin brothers Pedro and Margarito Flores on Jan. 27 were the latest to be sentenced in a series of high-profile federal cases targeting the Sinaloa Cartel's operations in Chicago. Accused of running a continent-spanning trafficking ring, they each received 14 years in prison after US District Judge Ruben Castillo agreed to sharply reduce their term in recognition of their work as government informants. Castillo called the Flores twins, natives of Chicago's West Side, the "most significant drug dealers" he'd dealt with in two decades on the bench, stating that they had "devastated the walls" of US national security by bringing at least 70 tons of cocaine and heroin into the country from 2005 to 2008. Prosecutors also charged the twins smuggled $1.8 billion back to Mexico—wrapped in plastic and duct tape. But it was federal prosecutors who pleaded for leniency, hailing the twins for gathering evidence against the Cartel's long-fugitive kingpin "El Chapo" Guzmán, who was finally busted in Mexico last year.

We recently noted that the ultra-puritanical ISIS has been burning the cannabis fields in the territory it controls in northern Syria—and that the cannabis farmers of Lebanon are arming to resist any ISIS incursion across the border. Now comes the hilariously predictable news that ISIS fighters may be snorting cocaine to keep their spirits up! On Jan. 6, the Kurdish Daily News posted a video from the town of Kobani in northern Syria, where local Kurdish fighters have been resisting an ISIS siege since September. The footage shows Kurdish fighters holding a stash of white powder in a big plastic bag just taken from the house of an ISIS commander. Kurdish fighters interviewed on camera said the house had been seized from an ISIS "emir" (as they call their commanders) who had earlier taken it over from local residents. The"emir" was killed in house-to-house fighting, and his home searched. In addittion to lots of weapons (of course), the coke stash was found. The Kurdish fighters said they believed the emir was distributing coke to his own followers to fuel their fighting spirit.

Amid peace talks in Havana, Colombia's FARC guerillas issued an angry communique Dec. 14, insisting "We are a rebel group, not narco-traffickers." This was in response to President Juan Manuel Santos' suggestion that FARC drug-trafficking could be considered a "political crime," potentially sparing guerilla leaders prosecution. This of course won Santos howls of outrage from the right; now he gets it from the other side. The FARC statement accused the government of trying to "confuse the minds of Colombians" with a "distortion," and decried the existence of a "capitalist narco-trafficking business" in the country. (El Espectador, El Tiempo, Dec. 14)

Reuters on Dec. 10 reported that the alleged Chicago jefe of Mexico's Guerreros Unidos narco-gang faces federal charges with seven others for a plot that involved moving heroin and cocaine to the Windy City in passenger buses. Pablo Vega Cuevas and his brother-in-law, Alexander Figueroa, both of Aurora, Ill., were arrested in Oklahoma; three suspected accomplices were busted in the Chicago area. Warrants have been issued for three others, including one believed to be in Mexico. The investigation led to the seizure of 68 kilos of heroin, nine kilos of cocaine and more than $500,000 in cash. "These arrests will have a significant impact on the supply and distribution of heroin and cocaine throughout the Midwest," Dennis Wichern, the DEA's Chicago special agent-in-charge, said in a statement.

The sentencing last month in a case related to the Sinaloa Cartel's Chicago connection provided further fodder for the increasingly plausible conspiracy theory that the DEA protected Mexico's biggest criminal machine. Federal Judge Ruben Castillo sentenced Alfredo Vázquez Hernández, who had been extradited after serving a sentence in Mexico, to 22 years in prison for shipping 276 kilograms of cocaine to Chicago hidden in railway cars. Federal prosecutors said Vazquez was a top-ranking operative of the Sinaloa synidcate, who arranged airplanes, submarines, trains and trucks to move cocaine from Colombia to Chicago via Mexico. Vazquez was characterized as a lifelong friend of the cartel's now-imprisoned top kingpin "Shorty" Guzmán. Judge Castillo said this hadn't been proved, but stated: "Given the amount, it's nonsensical to think this was this defendant’s inaugural voyage into cocaine trafficking."

Gregorio Santos, the populist president of Peru's Cajamarca region, was comfortably re-elected Oct. 5—despite being imprisoned as corruption charges are pending against him. The biggest issue in the race by far was the unpopular Conga gold mine project, majority-owned by US-based Newmont Mining. Peru's central government said it would recognize the victory, while his supporters marched in Lima to demand his freedom. Environment Minister Manuel Pulgar-Vidal called for a "political dialogue with all the actors" to resolve the crisis in Cajamarca. But Jorge Vergara Quiroz, president of the Cajamarca Chamber of Commerce, said that Santos' re-election created a climate of "uncertainty" that would discourage investment, and called on him not to take office. Segundo Mendoza, spokesman for Santos' Social Affirmation Movement (MAS), responded that the party respects private investment. He called on authorities to free Santos, saying he posed no flight risk.