An apparent chemical attack on the rebel-held town of Khan Shaykhun, Idlib governorate, left at least 80 dead April 4. After a bombing of the town, medics reported a "bloodless massacre," saying that they were treating people with symptoms including fainting, vomiting and foaming at the mouth. The hospital where gas-attack victims were being treated was itself bombed in the immediate aftermath, "bringing down rubble on top of medics as they worked," according to AFP. The opposition-run Health Department in Idlib has provided a list of the names of some 70 dead, with more still being identified. Some of the victims were brought across the border to Turkey for treatment, where several died. Turkish authorities say autopsies revealed evidence of exposure to sarin. The UN Security Council immediately called emergency talks on the attack. On April 4, US warships in the Mediterranean launched 59 Tomahawk cruise missiles at Shayrat air-base outside Homs, from where the Khan Shaykhun attack is said to have been launched. This constituted the first US attack on an Assad regime target throughout the course of the war (not counting last year's accident, immediately apologized for). (CNN, CNN, Jurist, BBC News, NYT, NPR)

Spain's top court on March 27 agreed to investigate claims by a Spanish woman who alleges her brother was tortured and murdered by Bashar al-Assad's security forces. According to the woman, who is identified only as AH for security reasons, her brother was executed in 2013 at a detention facility in Damascus. Spanish High Court Judge Eloy Velasco has asked Syrian authorities to appoint legal representation in Spain for the nine security officers implicated in the torture and murder of the litigtant's brother. The case is the first criminal complaint accepted against President al-Assad's security forces by a European court. The lawyers for AH contend that Spanish courts have jurisdiction over the complaint due to the woman's status as a Spanish citizen. Velasco determined that the complaint has standing in Spain's courts under international norms that consider family members of those who have "disappeared" as a result of international crimes to be equally considered victims of those crimes.

A suspected chlorine gas attack on an underground hospital in the rebel-held north of Syria's Hama governorate killed three people and injured dozens on March 25, as Assad regime forces attempt to drive back a rebel offensive in the area, local medical personnel told independent news website Syria Direct. A helicopter dropped a large yellow canister through the concrete roof of the Latamna Surgical Hospital, according to hospital personnel. Chlorine gas was then released, according to the account, spreading throughout the the underground facility. Trapped in the poorly ventilated facility, 35 people were injured—14 of them medical personnel—and three were reportedly killed, including a surgeon. "One of the victims smelled as if he just came out of a swimming pool," said Bilal Abdul Kareem of On the Ground News, reporting from the scene in the aftermath of the attack.

New evidence is deepening fears in the scientific community that the Middle East and North Africa risk becoming uninhabitable in a few decades, as accessible fresh water has fallen by two-thirds over the past 40 years. Already, per capita availability of fresh water in the region—encompassing 22 countries and home to nearly 400 million inhabitants—is 10 times lower than the world average. The region's fresh water resources are among the lowest in the world, and are expected to fall over 50% by 2050, according to the UN Food and Agriculture Organization (FAO). By century's end, higher temperatures may shorten growing seasons in the region by 18 days and reduce agricultural yields by up to 55%. "Looming water scarcity in the North Africa and Middle East region is a huge challenge requiring an urgent and massive response," said FAO director general Graziano da Silva on his recent visit to Cairo.

At least 33 people were killed in an air-strike on a school sheltering displaced residents outside the ISIS-held city of Raqqa, in northern Syria, according to monitoring activists on the ground. The behind-lines anti-ISIS monitoring group Raqqa is Being Slaughtered Silently, which has heroically reported on realities under Islamic State rule in the city, said the school at the village of al-Mansoura was sheltering some 50 families when it was levelled by air-strikes earlier this week. The raid is believed to have been carried out by US warplanes. "The massacres committed by [the] US-led coalition in Raqqa is unacceptable," the group said in a statement. "The international community must intervene to stop this." (The Independent)

The Kurdish YPG militia announced March 20 that it has agreed to the establishment of a Russian military base in Afrin canton in northwestern Syria. The YPG said Moscow will help train its fighters at the base. The Russian Defense Ministry denied plans for new military bases in Syria, but acknowledged that it has established a "reconciliation center" near the town of Afrin, in Aleppo governorate, officially tasked with negotiating pacts between anti-ISIS forces. However, YPG representative Redur Xelil said Russian troops are already arriving, with personnel carriers and armored vehicles. (EA Worldview, Haaretz)

More than 40 people, including women and children, were killed when an Apache helicopter fired on a boat carrying Somali refugees in the Red Sea off war-torn Yemen March 17. A coast guard officer in the Hodeidah area, controlled by Houthi rebel forces, told Reuters the refugees, carrying UNHCR documents, were on their way from Yemen to Sudan when they were attacked near the Bab al-Mandeb strait. The rebel-controlled Saba news agency accused the Saudi-led coalition of being behind the attack. The coalition immediately released a statement denying responsibility. While the International Organization for Migration said 42 bodies have been recovered, the death toll may be much higher. The UNHCR said 140 passengers were believed to have been aboard the vessel. 

The US military is denying reports that it bombed a mosque in northwestern Syria during evening prayers March 16, killing at least 50. There is even controversy over whether the Omar Ibn al-Khattab Mosque in al-Jinah (Jeena) village, Aleppo governorate, is still standing. The Pentagon admits to a an air-strike that supposedly killed several al-Qaeda militants in the village, which is held by Islamist factions including Ahrar al-Sham. The Pentagon released a statement saying the strike was "across the street from a mosque," with footage (supposedly taken minutes after the strike) showing that a mosque next to a destroyed building remained standing. (Al Jazeera, BBC News, Reuters) But Bilal Abdul Kareem, a US national who operates On the Ground News from northern Syria, recorded his own video from the purported bombing site. Kareem shows what he calls part of the "mosque compound" in ruins, and claims the mosque was operated by Jamaat Tablighi, a proselytization group that has hosted prayers there every Thursday for the past four years. (LWJ)